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GLP-1 Drugs Linked to Lower Colon Cancer Mortality
Researchers found that those taking glucagon-like peptide-1 (GLP-1) medications were less than half as likely to die within five years compared to those who weren’t on the drugs.
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CRISPR-Enhanced CAR T Cells Overcome Solid Tumor Barriers
Monash University researchers used CRISPR or a PTPN2 inhibitor to enhance CAR T cell function against solid tumors. Blocking PTPN2 improved T cell persistence and tumor killing in preclinical models, creating long-lived, stem-like CAR T cells.
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GLP-1 Drug Comparison Reveals Comparable Cardioprotection
Mass General Brigham researchers used real-world data to conduct a head-to-head study to investigate cardioprotective effects, finding both medications reduced risk..
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Low-Dose THC Eases HIV Drug Side Effects and Boosts Gut Health
Scientists found that long-term, low doses of THC reduced inflammation and liver toxicity caused by HIV and antiretroviral therapy. The treatment increased serotonin and healthy gut bacteria while lowering harmful bile acids.
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Pregnancy Paracetamol Use Not Clearly Tied to Autism or ADHD
Researchers say confidence in the findings of existing evidence is low to critically low, and suggest that any apparent effect seen in previous studies may be driven by shared genetic and environmental factors within families.
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Why Alzheimer's Patients Forget Loved Ones
New research has linked the loss of perineuronal nets in the brain to the loss of the ability to recognize loved ones, identifying a new drug target.
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Common Medications Linked to Adverse Breast Cancer Outcomes
New research has found that commonly used heartburn and blood pressure medications may interact with cancer therapies, influencing side effects and survival outcomes.
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Experimental Cancer Drug SU212 Suppresses Tumor Growth
A new molecule developed by researchers at Oregon Health & Science University offers a promising avenue to treat intractable cases of triple-negative breast cancer — a form of cancer that is notoriously aggressive and lacks effective treatments.
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Liver Organoid Developed To Study How Scarring Starts and Heals
Researchers at Science Tokyo have created a lab-grown liver organoid that mimics regeneration and scarring, offering a new platform to study fibrosis and test therapies that could reverse chronic liver damage.
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This New CBD Formula Actually Reaches the Brain
Researchers from the University of Rochester and Harvard Medical School developed a nano-micelle CBD formulation that rapidly reached the brain and relieved neuropathic pain in mice. The approach improved CBD delivery across the blood–brain barrier.
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