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Scientists Discover a New Phase of Ice: Ice XXI
Learn how the discovery of a new ice phase could open up new frontiers in exploring material phases and how matter behaves in extreme conditions.
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Model Predicts Drug Toxicity by Differences Between Preclinical Models and Humans
Discover how a machine-learning drug toxicity prediction model enhances the predictive power of AI in drug trials, boosting safety.
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Not All p53 Mutations Are Equal – Some May Help Guide Treatment
Researchers discovered that some p53 mutations, particularly R273H, overstimulate DNA replication and trigger immune activation through the cGAS-STING pathway. These tumors responded better to immunotherapy in mouse models.
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Scientists Identify 117 Enzymes That Control Gene Transcription
Researchers uncovered 117 enzymes that modify RNA polymerase II, the key enzyme that transcribes DNA into RNA. The study revealed that even cell-surface kinases like EGFR act within the nucleus to regulate transcription.
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Signaling Pathway Linked to Autoimmune and Inflammatory Damage
According to researchers, IL-15 triggers harmful T-cell activation, but the calcineurin–NFAT pathway acts as a brake, suggesting new therapeutic strategies for autoimmune and viral diseases.
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Blood Test for Heart Damage Could Help Predict Dementia Risk
Higher midlife troponin levels predicted faster cognitive decline and greater dementia risk decades later, suggesting a simple blood test could help identify those at risk.
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Rich and Poor Nations to See Drop Off in Crop Yields, Climate Dataset Warns
Rising global temperatures will dampen the world’s capacity to produce food from most staple crops – even after accounting for adaptation, according to new Human Climate Horizons data.
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New Technique Could Speed Up the Development of Gene-Edited Crops
Discover how a novel acceleration technique allows for the creation of transgenic and gene-edited crops without tissue culture.
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Space Dust Reveals Arctic Ice Conditions Before Satellite Imaging
Discover how particles from space can help researchers recreate Arctic ice conditions over the past 30,000 years.
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Immobilization Strategy Addresses Major Constraint of Membrane Protein Analysis
Learn about an effective immobilization method for membrane proteins, enhancing surface plasmon resonance techniques in research.
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