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Bubble-like chunks of ice at the edge of an ice sheet, above cold water.
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Scientists Discover a New Phase of Ice: Ice XXI

Learn how the discovery of a new ice phase could open up new frontiers in exploring material phases and how matter behaves in extreme conditions.
Doctor presenting a virtual capsule for drug safety in clinical trials.
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Model Predicts Drug Toxicity by Differences Between Preclinical Models and Humans

Discover how a machine-learning drug toxicity prediction model enhances the predictive power of AI in drug trials, boosting safety.
3D rendering of dividing cancer cells, illustrating the role of p53 in tumor suppression.
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Not All p53 Mutations Are Equal – Some May Help Guide Treatment

Researchers discovered that some p53 mutations, particularly R273H, overstimulate DNA replication and trigger immune activation through the cGAS-STING pathway. These tumors responded better to immunotherapy in mouse models.
Gloved hand editing a DNA strand with tweezers, illustrating RNA-based genetic modification.
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Scientists Identify 117 Enzymes That Control Gene Transcription

Researchers uncovered 117 enzymes that modify RNA polymerase II, the key enzyme that transcribes DNA into RNA. The study revealed that even cell-surface kinases like EGFR act within the nucleus to regulate transcription.
High-resolution microscopic image of a T cell with surface protrusions, essential for immune response.
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Signaling Pathway Linked to Autoimmune and Inflammatory Damage

According to researchers, IL-15 triggers harmful T-cell activation, but the calcineurin–NFAT pathway acts as a brake, suggesting new therapeutic strategies for autoimmune and viral diseases.
Anatomical heart model on a desk with a doctor writing in the background, illustrating heart damage.
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Blood Test for Heart Damage Could Help Predict Dementia Risk

Higher midlife troponin levels predicted faster cognitive decline and greater dementia risk decades later, suggesting a simple blood test could help identify those at risk.
A field of wheat, with a person's hand in the top half of the photograph. In the hand, they are holding several pieces of wheat.
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Rich and Poor Nations to See Drop Off in Crop Yields, Climate Dataset Warns

Rising global temperatures will dampen the world’s capacity to produce food from most staple crops – even after accounting for adaptation, according to new Human Climate Horizons data.
A person's hand hovering over a soil field. In their hand, they hold a small amount of soil with a seedling sprouting from it.
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New Technique Could Speed Up the Development of Gene-Edited Crops

Discover how a novel acceleration technique allows for the creation of transgenic and gene-edited crops without tissue culture.
A landscape photograph of breaking ice sheets in Arctic waters. Two people stand on a large sheet in the bottom-right of the photograph.
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Space Dust Reveals Arctic Ice Conditions Before Satellite Imaging

Discover how particles from space can help researchers recreate Arctic ice conditions over the past 30,000 years.
3D illustration of membrane protein structure representing immobilization methods.
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Immobilization Strategy Addresses Major Constraint of Membrane Protein Analysis

Learn about an effective immobilization method for membrane proteins, enhancing surface plasmon resonance techniques in research.
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