Latest App Notes & Case Studies
App Note / Case Study
Trace-Level Detection of Nitazenes in Dried Blood Spot Samples
This application note highlights a complete extraction-to-analysis method that offers the exceptional sensitivity and robust quantitation needed to analyze nine nitazene analogs and brorphine in DBS samples.
App Note / Case Study
AI-Driven Therapeutic Antibody Design
This application note explores how researchers successfully combined AI with advanced multiplexed gene synthesis to design and validate novel single-domain antibodies with atomic-level precision.
App Note / Case Study
Mass Photometry in a Forced Antibody Degradation Study
In this application note, discover how mass photometry can be used to analyze the fragmentation and aggregation of therapeutic antibodies in response to stressors like light, pH variations, and peroxide exposure.
App Note / Case Study
Mass Photometry, a Column-Free Orthogonal to SEC-UV
In this technical note, we explore datasets captured through mass photometry and size exclusion chromatography (SEC), comparing how they characterize the aggregation levels in different biosimilar antibodies
App Note / Case Study
Analyze Purity and Charge Heterogeneity on a Single Platform
This app note explores a how single multi-capillary, high-throughput platform can be used to perform both these techniques, enabling complex biotherapeutics to be rapidly and thoroughly characterized.
App Note / Case Study
Successful Scale-Up for High-Density Microbial Processes
This application note highlights the successful 5-fold scale-up of a high-cell density E. coli process from an established 200 L stainless steel fermenter to a 1000 L single-use system.
App Note / Case Study
Optimizing Metabolite Identification With Electron-Activated Dissociation
This app note highlights the advantages of electron-activated dissociation (EAD) in identifying oxidative metabolites of the molecular glue, mezigdomide.
App Note / Case Study
Ultra-Sensitive Quantification of Fluticasone Propionate
This application note highlights a LC-MS/MS method that leverages advanced sample preparation and next-generation detection technology to achieve high sensitivity and accuracy while minimizing sample volume requirements.
App Note / Case Study
Next-Generation Kinase Inhibitors: Overcoming Resistance and Enhancing Clinical Outcomes
This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for clinical use, and next-generation kinase inhibitors.
App Note / Case Study
Transform MSC Research With Real-Time, Non-Invasive Differentiation Monitoring
This application note demonstrates how combining live-cell analysis with high-throughput screening cytometry enables continuous, non-invasive monitoring of MSC differentiation, offering unprecedented insights into cellular dynamics while preserving
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